Other individuals are more likely to get serious Unintended effects simply because an exceptionally higher degree of morphine is manufactured. When you notice any of the subsequent Uncomfortable side effects, you should halt getting this drugs and request immediate professional medical assistance: sluggish or shallow respiration, confusion, sleepiness, smaller pupils, emotion or remaining Unwell, constipation, lack of hunger.

Codeine could become additive when taken long run. Over a lengthy period of time, lots of people could become depending on codeine or knowledge indications of withdrawal when halting it.

A serious condition named metabolic acidosis (a blood and fluid abnormality) has become documented in individuals in these circumstances when paracetamol is used at standard doses for a prolonged period or when paracetamol is taken alongside one another with flucloxacillin.

That you are taking medicine to deal with depression termed MAOIs (monoamine oxidase inhibitors) or have taken them in the final 2 months. MAOIs are medicines for example moclobemide, phenelzine or tranylcypromine.

It is important to browse the affected individual leaflet of your medication for an entire list of Unwanted effects and cautions.

•    You have a bowel dilemma like colitis or Crohn’s ailment or perhaps a blockage of your bowel.

Administration to nursing Females is not really advised as codeine could possibly be secreted in breast milk and may result in respiratory despair in the toddler.

If you are not certain if any of the above implement to you, check with your physician or pharmacist in advance of having co-codamol.

If you will get any side effects, discuss with your doctor or pharmacist. This involves any probable Unwanted effects not mentioned Within this leaflet. It's also possible to report side effects specifically via the Yellow card Scheme at: or hunt for MHRA Yellow Card during the Google Play or Apple App Shop. By reporting Unwanted effects, you may help deliver more information on the safety of this medicine.

Each individual suffering from Continual pain has a singular personal practical experience when having co-codamol tablets to be a treatment.

Speak to a doctor at the same time if you're taking an excessive amount of of this drugs Even click here when you come to feel nicely. This is due to excessive paracetamol could cause delayed, serious liver problems.

Some medicines interfere with how co-codamol performs. And co-codamol can interfere with the way in which some medicines perform. Inform your physician if you are taking:

Don't just take co-codamol with paracetamol, or other medicines that comprise paracetamol. Co-codamol currently is made up of paracetamol so you could potentially be vulnerable to paracetamol overdose.

CYP2D6 inhibitors Codeine is metabolised because of the liver enzyme CYP2D6 to its Lively metabolite morphine. Medicines that inhibit CYP2D6 activity may well decrease the analgesic outcome of codeine.